States » SouthPosted at: Nov 13 2026 8:08PM


VIT-AP researchers develop promising low-cost photonic technology for disease screening

Vijayawada, Nov 13 (UNI) In a significant research initiative, scientists from CATS Global (CASTLE Advanced Technologies and Systems), Nashik, Maharashtra, and VIT-AP University, Amaravati, Andhra Pradesh, have developed and experimentally demonstrated an innovative, low-cost optical sensing approach that could pave the way for affordable, non-invasive disease screening through breath analysis.
The research, authored by Prof. Dr. Rao Tatavarti, Prof. Dr. Sridevi Nadimpalli and Prof. Dr. P. Arulmozhivarman Pachiyappan, was published on November 6, 2026, in the prestigious international journal Scientific Reports, published by Springer Nature, according to a press release issued by VIT-AP University on Friday.
The research article, titled Photonic elastic-backscatter fingerprinting of exhaled-breath metabolites for non-invasive disease screening explores an innovative photonic sensing technique that uses a simple, low-power laser and a position-sensitive optical detector to identify distinctive optical signatures associated with disease-related chemical compounds.
A New Direction in Affordable Breath-Based Screening Human breath contains hundreds of volatile organic compounds (VOCs) and other gases that can reflect changes in the body's metabolic processes. Variations in the concentration of these compounds can be associated with different diseases, making breath analysis a promising approach for non-invasive health screening.
Conventional breath-analysis technologies often rely on sophisticated laboratory instruments including mass spectrometers, gas chromatographs and advanced optical spectroscopy systems, which can be expensive and require specialized infrastructure.
The study demonstrates the potential of photonic elastic-backscatter fingerprinting to detect, distinguish and classify different disease-associated gas mixtures through subtle changes in the intensity and spatial position of scattered laser light. This approach offers an exciting direction towards developing compact, cost-effective and potentially portable optical sensing systems.
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