States » SouthPosted at: Nov 10 2026 11:39PM


Hyderabad surgeon develops US-patented heart valve to prevent blood clots

Hyderabad, Nov 10 (UNI) Heart surgeon Dr Lokeswara Rao Sajja of the Sajja Heart Foundation has developed a novel heart valve designed to prevent blood clot formation, potentially eliminating the need for lifelong blood-thinning medication among patients undergoing mechanical valve replacement.
The new heart valve, which has received a US patent, has shown promising results in animal experiments, with the valves remaining free of blood clots for more than five months without the use of blood-thinning drugs, the foundation said in a release on Tuesday.
The findings have been published in two reputed international scientific journals, Nature Scientific Reports and PLOS One.
Currently, patients whose heart valves are severely damaged often undergo replacement with mechanical valves. However, such valves carry a risk of blood clot formation, requiring patients to take blood-thinning medication throughout their lives. These drugs can increase the risk of bleeding and cause other complications.
The risks are particularly significant for pregnant women and athletes, as the medication may affect pregnancy and restrict participation in sports.
Patients also require regular blood tests and must follow several lifestyle precautions.
Dr Sajja said the experimental results were encouraging and could have significant implications if confirmed through human clinical studies.
"If these results are confirmed in human studies, such valves could free patients from lifelong blood-thinning medicines. This would especially help young patients, who need long-lasting valves, as well as pregnant women and athletes," he said.
The development could mark an important advance in heart valve replacement technology, particularly for patients requiring durable mechanical valves without the complications associated with lifelong anticoagulant therapy.
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